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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0ad37952f3618f7023c5d3c3130f59cd96c3e5e5ce4bcc770cb9fbc829fe311' 
  AND token = '+rnhzQgyCYYa6OUXEvIhJ11zHuO1pAqGj18eRZK0SNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}