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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67115bb674dd59c68a160b8d010985374097c012c17764d08f0111b24da078f2' 
  AND token = 'tlIqw5M4/P0Kj1Kx4cFTEtzd7NczCN3ivo7TSyaJ94g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}