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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd1f7a8b63bd43173be6fe1e0efd01481de2f705c359b118fa010c6bb9809f0' 
  AND token = 'z4wt0W1ELZbAJcvv52phPjJCMRq5MkONLyW9RBSzMMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}