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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82cacc0f6e6b9b8b121a054d80cb75631cb5cb78f19ed0c601df5fd42f456cac' 
  AND token = '+zdteAb77+Rnq8acKLRnu/+rVeq4dtRgIlKLFsyxxPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}