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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc443684352e0d3b2c128d24aeeb062e5c940fb5b62de7db3666bcbfe283a10' 
  AND token = 'NvMakwZaH3Y9XUVVzHBpKt17/2TlpW7I8VqxYZ3mW54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}