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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7b3f6f824e69db2047f60db701193fe5fb91bbe007280b4d3742ba97fd432f1' 
  AND token = 'GO+BibKyICAGJOa47mTmFxrHUtZ58eOauh772c2K7I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}