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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d991caa9b04d0db2486c6dc340b8dcc969bbbfbe0c8af746fe6b42781afb85' 
  AND token = 'NiferTM4hcqE3sHdrczhQgpqMbYdUp5C3igJumctJTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}