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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e4ba4e8ed3f2dcc0a4b82445c72d67a276ba4cc00f87831c3671f6e7aa3843' 
  AND token = 'OyAisSN7Tr5chgzMlpIyD3901HnrDQjAHk6rQAHQmm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}