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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a9d9137aa2fb2779977c01ab09be619def8d9dd5b74b64f0ff2641675d9d3d8' 
  AND token = '7t6/Cswh+Vp+0zdDE4Iu1PlD3F3rbgQqx/D2N1RgLJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}