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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '322b4db0ee46c4b78ecddb6e4757ddb04a44fd9832cded3aa170c90d957f7c32' 
  AND token = '+tDSF7ThhVlBoqpMJgVKaOp/xmqy+oVf1FbJsLMCnJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}