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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2345588e669a81e26405833713972c5806f6e4efa2ad9212102c581b095b289' 
  AND token = 'G3hd5Pu9DZBB3HzKgDvx6iqeK5EZ2jB4yPp25kNztzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}