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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6523ac60ed014c5c9e1f5214836551e6861fdab34031786a08cad265371faed' 
  AND token = 'bwIyMF+Pw280aH2DJ8qGeAmY17qQ8xxMcE0wc3KHwXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}