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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef3a69e7afa137f64ef721a5441aa6955a1504ac5c69c4160ce41d63d7422811' 
  AND token = '4ya//J0n2ymw/AuvBlxjuMOfj9jk2t2th5ARU1EW7oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}