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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '778448d84c5bdf3c6732f76894436ee7434da5b8e7796fa6111bb1b054768686' 
  AND token = '8vLOhrWaQBxT4gqvONEjDFGINyUxqqnTNixdDma/P9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}