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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644d35c25c3a371a6a183d16472a6c174757c0f287b777aec5f0157824407773' 
  AND token = 'E3Sx9tp7HgdolM9SykRWqUT4QpYWTHiqlxMEr2A7QYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}