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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e4238b80d18f75998da2b0563c0dc16dc64a67f22c139e063abe75cf5ea404a' 
  AND token = 'cWuCh2586IE/jWYy9lDBrfGcMvK0Xt6Z30H0UugC4q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}