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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83be47b6d570a17fce07fa9f53210474fe73d3fbf949633638050f2c9ae60700' 
  AND token = 'V8rs26gY/GxTDBOUppRz/uOaBN1pV8C89OATIkNNTpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}