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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a74ce7d75c0fc9fda579531dd721df1b61e2b7c80884fe2c792c04f54c0c3f7c' 
  AND token = 'XUIUR1WOHQ1O7hwG9Yc1rUqoKuEPMcSksQMchqY01Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}