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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df0f7af36f7cdf24a9a3b2a1abdea0969bc214d7a4238f3b903dede25579d18' 
  AND token = '4t5kr3kR3kbicmNYjSZgQWkhRCG8AYZQHyo7Ohh+QTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}