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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f146630cf68919e021d3052f3930b0ae57ee2baca3964f6d51b270e36910c7be' 
  AND token = 'Z3RMokM3bBt+Hx5RSus70km5PJ8sdLn1eTRfLgm7KCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}