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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efbbe4177a6002b179070b55739251da90eb9ff149286d4876a0b2de1ccd0137' 
  AND token = 'XnDSiDLCGnD9DTVjDWy6cvmE4DDoWG017dWb++CTMCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}