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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '515458e735d930ec12b590c36608133a186d73eea4f48bf07031ce520d6764da' 
  AND token = 'W8DcRXhY3wTYZvrwDatSbNJ2y8GJ8cjBChVuS7Oh+bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}