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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d24ac300040b82c9f3d9df9c29fe360bcc53db379b281dbcaa346f1e8389f95' 
  AND token = '30DLn0BbF2qI24oXY/2P5tELeyhbENWhmPgTWEHbEHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}