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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f151a52d50b1ba415032ed9374fb647226c6e021ac3039b5d2955e3b92701776' 
  AND token = 'ZaP2jKE+ZkyEljYHA+or34lMk1tB6ZVOxrKzmtTHqxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}