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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '538cc6d08b1528237719c74120554d078c0d9167222d160c4f309e3fb0b4cf59' 
  AND token = 'Pb2Bz5MAQlPb1T/URmRM7N5KJE6OaDxXnFwfGFm2VkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}