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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e730a0845117496ec0f3dd6ae6d507390112a885ef2c64b07ce4cf5eaa8b63' 
  AND token = 'TIYh9lCIbCd+XjLNfKCAkf5ffHb9+8Kvyo0Vn/r6NoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}