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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '585f12410c99c19b0a469fefb713b6dc270bfaa21ea81768035eaacc8e6318cf' 
  AND token = 'E2VWAhntwAK81b/3T3py+80spiTvswl4206EfekpJBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}