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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c73a1cd91918cf3dc020e0246586efaf80dd69e567b020519482769b5a3b27' 
  AND token = 'SarQY71To6wjjJLXEDcvldetRHQLyblyR5gLrFSHX6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}