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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3e80c58a38e51b239cabf59e159b028053c55be2da3eb6a6c13d3f1017de59' 
  AND token = 'w/QvPd+jjlApTjfIbdhLxPiOiW3RkSVqZJ69RXoo4sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}