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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273e3a928cc0a23f0d54ed6f78aad591df59421a6b7ee119f0ebd8e578ec163f' 
  AND token = 'zSbaHdtRzhZ/wSN+3kJBoLzbvgPLgW/wEHeHRIOxxNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}