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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28addd2cf0c372f962232c8ebe8dcf8c844b1cb0fee49cf1b63ff209b322de29' 
  AND token = '4EgTKjViIqEJQORailh0skOHwe0qvPlHulgkBny+CiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}