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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fabc05cd7aac97f86bc9697a6f212016157822ffda81fa7d38a6fc0c47400d8' 
  AND token = 'Ze6tmgk4s3skvb/JcupfEld3Nzk32YFoMcUyp3hvNWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}