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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f506bcfb8c2c3e704b8da41f54a4ee06a3e0e2477894faf37dccf1d370f9bc' 
  AND token = 'efK0ut/u58INbbGWa+uOYaIc4KU7Vi9QktDsmIs0Pcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}