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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc40bb12844eb024746ce3bb9e900d06897e15e06b336f8a91d5e6df3fd43658' 
  AND token = 's0+d3+BwmimP3sihFKZoHNiZplaI22kjkFsVACdQzmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}