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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63b4bb445084408ff7e6b704e64e0ea09da9f631da7a1230ddefece3de84fdf4' 
  AND token = '0d9FTUw+J12HAI9qLlpXZ/IrF09QwTkb7Aa4g8/LKqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}