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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3bd7a3dcd7a33ec59f1d25be3e316686a5084bae4b5a253d70b3e33f481f09' 
  AND token = 'PqNySjzjpD67HotuX/XjIfGTACEIAa6GK0pScTkjHnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}