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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e546a882bea9c2939c2c8bcceced020b7cc7f2f5e73f67657b033270eca0781c' 
  AND token = 'Q8MH4pqRIX5NAyTTXZKafmVMv3yv7DEmfx0yeoMOmdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}