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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23190afe1e981bef9959da64447db537f5d0211adb1e9ac4d4c6554322d7afe4' 
  AND token = 'mDGCdZvvi4Q7kFxUy2qvy/t/Y7f+twqdbPbkLHJChOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}