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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14787f922ecd6c3d2d8cebbffb93ed6c05c9cf10d3207687d148462b2a25f774' 
  AND token = '9hYGeoVyopL2W0pGByr0mu96SkJLoOegtwecpzEJFzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}