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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17b435d30cd1f425db7d46929b04f1aad214a645e05015f200926074ba9de4b7' 
  AND token = '+rUAPl1QgJXkAEV1KL6i1QiBFymgvzq9qgu36sKkkQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}