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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd10dc8cfd1d27812378986a7adc52feedc0892cb94f30357975e5bb86c9e8b2' 
  AND token = 'e8TJEUg6u/TD4ufbisFis83sU1dfp1UU6akb2tn6CHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}