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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b69d4f0c3dec76a71455c0afe5b4dd96d0ce81a68f69c8b32b018b8a130885' 
  AND token = '9azMe5Rct5f2LkEf6owtHVw+CdcUQyK3OP19Ct/YKaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}