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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb408b64c8b1807526bfa462d4e7eda1b192ad0713a8e86f690d1721f8a6d208' 
  AND token = '6qdkAeoDLy1scEK9B1pmK4gAe5bkUbPkZyPvdd3fTkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}