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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d8a65a49ed32b6a8885a96238ec70964b5cdfbb293eb84b13f59a460864bf84' 
  AND token = 'fAK0bJSQuzniDZ8Zw7wh4F4M2rkQw/fW0dhEbVt71HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}