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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc10d64858c4b03697999bae5aaa5daa7e36978a62f7b9a38e97084b1c311c00' 
  AND token = 'ApcxxP43uA2atO5vj1xGYm3S93ZO52RMFYIFzfiNkzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}