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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68b7b9f6159c9afa081ae120a7565a38ad2f706d57b6810c9ce65d2aa929abb3' 
  AND token = 'aTqbPAYar8plsPc5NB/lpPLSenjBxYSfRMr3zZbhMJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}