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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485c7ba6edb70e8ed0ba0de38493bd48c2ddb88c3510d38967bbd954cc7b4945' 
  AND token = 'M7WbgcE53EKgDOiyS0OXU8fJHEC0WvYo56x1L3+qKdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}