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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80397e846d4d99da595f343990c8e2f19daaf378f42252035c6f00972346c63e' 
  AND token = 'o4etdZ/fZAzWM/rt32IZIJAW42Rzbk2HNatE14YwQ8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}