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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13a686818c66fac16ca1e55faed827f166f01a06439df4b33d6c508e50fdceab' 
  AND token = 'VxUavldhB7VFix71dtPQ7FmD5WDAgbKY54fP3SDbWAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}