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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491b6b6ab30c34fa06cd4d0a09d9ea6d0597389fc9cd567b1294a2d4f7751682' 
  AND token = 'YJrfoE8kysIPaTIplRGxVIpYa5xp9P6gWpOq+VmgMgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}